Journal alert: Sigma-metrics in CCLM
Posted by Sten Westgard, MS
Clinical Chemistry and Laboratory Medicine just published an article where I am a co-author:
Sigma metrics used to assess analytical quality of clinical chemistry assays: importance of the allowable total error (TEa) target. Koen Hens, Mario Berth, Dave Armbruster, Sten Westgard. CCLM. Volume 12, Issue 7, 973-980.
We looked at three high volume chemistry analyzers in the AML reference laboratory in Belgium, and calculated Sigma-metrics for 25 basic chemistry tests at 2 different levels, and further assessed them using three different sources for allowable total error: the CLIA specifications, the German Rilibak rules, and the biologic variation desirable specifications ("Ricos goals"). For those who like tables and data, this study has a lot of it. That's 450 different Sigma-metrics we calculated.
The biggest finding was how different the different sources of allowable total errors are. Choosing the right target is critical in determining your Sigma-metric.
Some of this data will also be presented at the IFCC conference in Istanbul next week.
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For over 25 years, WESTGARD QC has provided the latest news, education, and tools in the quality control field. Our goal is to bring tools, technology and training into today's healthcare industry — by featuring QC lessons, QC case studies and frequent essays from leaders in the quality control area. This is also a reference source for quality requirements, including CLIA requirements for analytical quality. This website features the best explanation of the Multirule ("Westgard Rules") and how to use them. For laboratory and healthcare professionals looking for educational and reference material in the quality control field.
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