Sigma Metric Analysis
In March 2010, the Centre for Evidence-Based Purchasing (CEP) in the United Kingdom released an evaluation report: Point of care tests for the measurement of blood creatinine. The Guildford Medical Device Evaluation Centre (GEMC) evaluated the performance of multiple devices. In addition to highlighting some of the findings, we add Sigma-metrics calculations and Method Decision charts.
An abstract from the 2010 AACC/ASCLS meeting compared Three POC Analyzers for HbA1c. Given the recent study from Lenters-Westra and Slingerland (where 6 out of 8 analyzers couldn't meet the standards for analytical performance), how do these three devices fare?
A recent evaluation in CCLM of the Menarini/ARKRAY ADAMS A1c HA-8180V analyzer gives us another opportunity to see if current performance on the market can meet the tightening requirements for HbA1c.
In a 2008 issue of Annals of Clinical Biochemistry, a study looked a seven different 25-hydroxyvitamin D methods, compared with liquid chromatography-tandem mass spectometry. Using quality requirements developed by and derived from Stockl, Sluss, and Thienpont, we examine this methods with Sigma-metric analysis.
In a 2009 issue of Annals of Clinical Biochemistry, a study takes on two Point-of-Care HbA1c devices using two different reference methods. Both POC methods are standardized to the IFCC reference system and aligned to DCCT standards via the National Glycohemoglobin Standardization Program (NGSP). Both reference methods are also standardized against the IFCC reference method and traceable to DCCT and NGSP. If everything is standardized and traceable, there can't be any problems, right?