Sigma Metric Analysis
We take a look at a new direct enzymatic method for %HbA1c.
Elevated concentrations of homocysteine (Hcy) are clinically associated with disorders and cardiovascular disease. A recent paper compared six different methods for this important analyte. But in the absence of a CLIA quality requirement, how can we compare performance?
At the 2008 AACC/ASCLS convention, a poster was presented for a new direct enzymatic assay for %HbA1c. How does it stack up against HPLC and immunoassay methods? How do you judge a method when you've got multiple comparison methods and multiple quality requirements?